A NEW INDOLE DERIVATIVE, LWX-473, OVERCOMES GLUCOCORTICOID RESISTANCE IN JURKAT CELLS BY ACTIVATING MEDIATORS OF APOPTOSIS

A New Indole Derivative, LWX-473, Overcomes Glucocorticoid Resistance in Jurkat Cells by Activating Mediators of Apoptosis

Background: Glucocorticoids (GCs) are commonly used as the primary chemotherapy for lymphoid malignancies, including acute lymphoblastic leukemia (ALL).However, the development of GC resistance limits their prolonged use.Methods: In this study, we investigated the potential of a newly synthesized indole derivative called LWX-473, BACKPACKS in combi

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Green waste characteristics and sustainable recycling options

Green waste is a diverse mixture of biomass mainly generated through site clearing and landscape maintenance in inhabited areas, which requires appropriate management to address sustainability concerns.However, the recycling potential and technological applicability of green BREAST/NIPPLE waste remain poorly understood possibly due to limited knowl

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